Opportunities For Pharmacogenomics and Personalized Medicine
52:31
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3 years ago
Google TechTalks
February 23, 2006
Russ B. Altman
Prof. Altman is the director of the Center for Biomedical Computation at Stanford University and is director of the biomedical informatics training program. He is also the principal investigator of a project, PharmGKB, which is an online database of genetic and phenotype information from people who have participated in research studies at various medical centers participating in the PGRN.
ABSTRACT
Pharmacogenomics is the study of how variation in human genes leads to variation in drug response. One of the major promises of the genome project was to improve medical outcomes for patients by using knowledge of their genetic background. The PharmGKB (Pharmacogenomics & Pharmacogenetics Knowledge Base, http:// www.pharmgkb.org/) is an NIH-funded resource at Stanford University charged with supporting the research community in pharmacogenomics, by storing both genetic variation information and drug-response information, building tools to help scientists visualize and analyze the data, curating the pharmacogenomics scientific literature (both manually and through text processing algorithms), representing pathways of genes that work together to affect drug response, and providing expert annotation of current pharmacogenomic knowledge.Google TechTalks
February 23, 2006
Russ B. Altman
Prof. Altman is the director of the Center for Biomedical Computation at Stanford U...all »Google TechTalks
February 23, 2006
Russ B. Altman
Prof. Altman is the director of the Center for Biomedical Computation at Stanford University and is director of the biomedical informatics training program. He is also the principal investigator of a project, PharmGKB, which is an online database of genetic and phenotype information from people who have participated in research studies at various medical centers participating in the PGRN.
ABSTRACT
Pharmacogenomics is the study of how variation in human genes leads to variation in drug response. One of the major promises of the genome project was to improve medical outcomes for patients by using knowledge of their genetic background. The PharmGKB (Pharmacogenomics & Pharmacogenetics Knowledge Base, http:// www.pharmgkb.org/) is an NIH-funded resource at Stanford University charged with supporting the research community in pharmacogenomics, by storing both genetic variation information and drug-response information, building tools to help scientists visualize and analyze the data, curating the pharmacogenomics scientific literature (both manually and through text processing algorithms), representing pathways of genes that work together to affect drug response, and providing expert annotation of current pharmacogenomic knowledge.«
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